Electrical Stimulation Promotes Motoneuron Regeneration without Increasing Its Speed or Conditioning the Neuron
نویسندگان
چکیده
منابع مشابه
Electrical stimulation promotes motoneuron regeneration without increasing its speed or conditioning the neuron.
Motoneurons reinnervate the distal stump at variable rates after peripheral nerve transection and suture. In the rat femoral nerve model, reinnervation is already substantial 3 weeks after repair, but is not completed for an additional 7 weeks. However, this "staggered regeneration" can be temporally compressed by application of 20 Hz electrical stimulation to the nerve for 1 hr. The present ex...
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Functional recovery is often poor despite the capacity for axonal regeneration in the peripheral nervous system and advances in microsurgical technique. Regeneration of axons in mixed nerve into inappropriate pathways is a major contributing factor to this failure. In this study, we use the rat femoral nerve model of transection and surgical repair to evaluate (1) the effect of nerve transectio...
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That human body generates biological electric field and current is a well-known natural phenomenon. In 1983, electrical potentials ranging between 10 and 60 mV at various locations of the human body were measured by Barker (Foulds & Barker, 1983), who also located the so-called epidermal or skin “battery” inside the living layer of the epidermis. Naturally occurred electrical field in human bod...
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The peripheral nervous system has the intrinsic capacity to regenerate axons into target tissues, and peripheral nerves severely damaged or transected can be reconstructed by microsurgical techniques. The aim of peripheral nerve surgery is to pave way for fast and most possible thorough functional recovery. However, full functional recovery is rarely seen and several reasons for this have alrea...
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We introduce three implantable tissue regeneration systems; an implantable cell graft culture system, an implantable electrical stimulation system for bone regeneration, and a liquid crystal polymer (LCP)based bone regeneration device. These devices allow electrical stimulation to stem cell grafts under in vivo circumstances. After a cell culture using the implantable cell graft culture system,...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2002
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.22-15-06631.2002